Sam Adams (born June 13, 1973 in Houston, Texas) is an American football defensive tackle who currently plays for the Buffalo Bills. He was drafted out of Texas A&M by the Seattle Seahawks with the 8th pick in the first round of the 1994 NFL Draft.

He previously played with the Seahawks (1994-99), the Baltimore Ravens (2000-01, winning Super Bowl XXXV in 2000), the Oakland Raiders (2002, losing Super Bowl XXXVII) and the Buffalo Bills (2003-present).

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Sam Adams Sr. is the father of Sam Adams, and as the son is now, was formerly a professional football player, playing at guard with the New England Patriots (1972-1980) and New Orleans Saints (1981).