Regina Marsikova (b. December 11, 1958) was a successful Czechoslovakian tennis player, winning 5 singles titles and 12 doubles titles. Her single titles were at Rome, Toronto and Christchurch in 1978, Phoenix in 1980 and Berlin in 1981. In Grand Slam competition she never went further than the semi-finals (three, all at the French Open, 1977-79).

Her major doubles win was at the French Open in 1977 with Pam Teeguarden