Piero di Cosimo (also known as Piero di Lorenzo) (1462-1521) was an Italian painter. The son of a Florentine goldsmith, he apprenticed under Cosimo Rosseli , whom he assisted in the decoration of the Sistine Chapel. He was noted for his rather eccentric personality and unorthodox interpretations of mythological subjects. He also wrote a relatively famous treatise on geometry. Piero's students included Andrea del Sarto. He was found dead at the foot of a flight of stairs.

His works include:

• Portrait of Simonetta Vespucci (c. 1480)
• The Visitation with Saint Nicholas and Saint Anthony Abbot http://www.nga.gov/cgi-bin/pinfo?Object=508+0+none (c.1490) painted as an altarpiece for the Capponi chapel in the church of Santo Spirito, Florence
• A Satyr mourning over a Nymph http://www.nationalgallery.org.uk/cgi-bin/WebObjects.dll/CollectionPublisher.woa
  /wa/work?workNumber=NG698 (c.1495)
• The Discovery of Honey by Bacchus http://www.worcesterart.org/Collection/European/1937.76.html (c.1499)
• Allegory http://www.nga.gov/cgi-bin/pinfo?Object=304+0+none (c. 1500) (oil on panel)
• The Nativity with the Infant Saint John http://www.nga.gov/cgi-bin/pinfo?Object=518+0+none (c. 1500) (oil on canvas)
• Fight between the Lapiths and the Centaurs http://www.nationalgallery.org.uk/cgi-bin/WebObjects.dll/CollectionPublisher.woa
  /wa/work?workNumber=NG4890The (c.1500-15)
• La Maddalena http://www.galleriaborghese.it/barberini/it/maddalen.htm (1501)
• The Return from the Hunt http://www.metmuseum.org/collections/view1.asp?dep=11&full=0&item=75%2E7%2E1 (c.1505–7)
• Perseus Frees Andromeda http://www.arca.net/uffizi/img/1536.jpg (c.1513) (oil on wood)
• The Building of a Palace http://www.ringling.org/pages/art_museum_collection_8.htm (c.1515/20) (Oil on panel)
• Frescoes in the Sistine Chapel of Moses and the Tables of Law and Sermon on the Mount and Healing of the Leper.

Giorgio Vasari includes a biography of Piero di Cosimo in his Lives of the Artists.