Mtutuzel Dudu Pukwana (18 July 1938 – 30 June 1990) was a South African saxophone player, pianist and composer.

Along with Mongezi Feza, Nick Moyake , Johnny Dyani and Louis Moholo, he was a member of Chris McGregor's group the Blue Notes. As mixed-race groups were illegal under apartheid, the Blue Notes emigrated to Europe in 1964, and eventually settled in London.