Many real people and fictitious characters share the name William Wilson, including:

• William Bauchop Wilson, the first United States Secretary of Labor
• William Griffith Wilson, co-founder of Alcoholics Anonymous
• William L. Wilson, Scottish nationalist
• William Lyne Wilson, a Postmaster General
• William Wilson, a British Labour MP before 1983
• William Wilson of Pennsylvania, Member of the House of Representatives 1815-1818
• William Wilson of Ohio, Member of the House of Representatives 1823-1828
• William Wilson , author of An Incomplete Education

• "William Wilson" is a short story by Edgar Allan Poe.
• Admiral William Wilson , a character in the 1999 film Wing Commander