William Talbot, 1st Earl Talbot (16 May 1710–27 April 1782) was an English nobleman.

Talbot earned the title of Baron Talbot of Hensol at his father's death in 1737. He was Lord High Steward at King George III's coronation, and became a member of the Privy Council in 1761. He was created Earl Talbot in the same year (the subsidiary title of Viscount Ingestre was attached). At his death, the earldom became extinct, while the barony passed normally.