Ragusa can refer to:

• The present city of Ragusa in Sicily, Italy
• The historic name of the city of Dubrovnik, Croatia. The Ragusan Republic was the most important and the most independent Dalmatian maritime city state, with varying levels of sovereignty in the period between 1358 and 1808.
• A Swiss chocolate confectionery with truffle filling and whole hazelnuts, produced by Camille Bloch SA.