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Quinolone

(Redirected from Quinolones)

Quinolones or fluoroquinolones are a group of broad-spectrum antibiotics.

Fluoroquinolone antibiotics are highly potent and considered relatively safe. However, they can have potentially troublesome side effects. For example, case reports have implicated their use in rare instances of tendon damage, especially when administered with a systemic corticosteroid.

Mechanism

Quinolones act by inhibiting the bacterial DNA gyrase enzyme.


Examples

External links

  • Fluoroquinolone-Induced Tendinopathy: What do we know? Richard M. Harrell, MD. http://www.sma.org/smj1999/junesmj99/harrell.pdf


Last updated: 02-08-2005 14:24:42
Last updated: 05-02-2005 00:54:20