QC can stand for:

• Quake C is an interpreted scripting language implemented in the computer game Quake by ID Software
• Quad Cities, a group of five cities on the Mississippi river, on both sides of the Iowa/Illinois border.
• quality control
• Quebec (Canada Post provincial abbreviation)
• Quebec Central Railway
• Queen Consort
• Queen's Counsel
• queer but correct, a notation used in copyediting that signifies an unusual-looking spelling or word usage has been double-checked. Sometimes CQ (correct if queer) is used.