*This article is not about the symbol for the set of prime numbers, ℙ.*

The **prime** (′, Unicode U+2032, `′`

) is a symbol with many mathematical uses:

A **double prime** (″, Unicode U+2033, `″`

) is the equivalent of two prime characters, and is used for similar purposes:

As an extension of the above symbols, the **triple prime** (‴, Unicode U+2034) and **quadruple prime** (⁗, Unicode U+2057) are often used to indicate the third and fourth derivative of a function, respectively. (Not all Web browsers can display these symbols.)

To avoid counting the number of primes, the notation *f*^{(n)}(*x*) can be used to mean the *n*th derivative of *f*(*x*) when *n* is large.

## Non-mathematical uses

The prime can also be used in the transliteration of some languages, such as Russian, to denote palatalization.

In the study of momentum in physics, the prime is used to denote variables after an event. For example, v_{A}' would indicate the velocity of object A after an event.

In molecular biology, the prime is used to denote the positions of carbon on a ring of deoxyribose or ribose. The prime distinguishes places on these two chemicals, rather than places on other parts of DNA or RNA, like phosphate groups or nucleic acids. Thus, when indicating the direction of movement of an enzyme along a string of DNA, biologists will says that it moves from the 5' end to the 3' end, because these carbons are hanging from the ends of the molecule. Prime can also be used to indicate which position a molecule has attached to, such as "5′-monophosphate".

## Representations

The prime symbol should not be confused with the apostrophe (', Unicode U+0027) or acute accent (´, Unicode U+00B4); the double prime should not be confused with the quotation mark (", Unicode U+0022).

When the character set used does not include the prime or double prime character (e.g. ISO Latin-1 is commonly assumed on IRC), they are often respectively approximated by normal or italic apostrophes and quotation marks.