Omega is the name of various medium-format cameras. The Simmon Brothers built the original Simmon Omega cameras in the United States. These rangefinder cameras took photographs on 120 roll film. Later, Konica manufactured the Koni Omega line. The last models, including the Rapid Omega 200, came from Mamiya. This line had interchangeable lenses, including a 58 (or 60) mm wide-angle, a 90 mm normal lens, a 135 mm portrait lens, and a 180 mm telephoto. A close-up adapter was popular with wedding photographers.

Another line, the Omegaflex, was a twin-lens reflex camera. Its lenses and accessories were not interchangeable with those from the Omega line. The Omegaflex took 6 cm square pictures on 120 roll film.