National Wildlife Refuge is a designation for certain protected areas of the United States managed by the United States Fish and Wildlife Service.

National Wildlife Refuge system is a network of lands and waters managed to protect wildlife and wildlife habitat. The system consists of over 500 refuges across the nation.

Nearly all of them have the words "National Wildlife Refuge" in their names; exceptions include

• Sully's Hill National Game Preserve
• Desert National Wildlife Range
• Fort Worth Nature Center and Refuge
• National Elk Refuge
• Hart Mountain National Antelope Refuge
• Ouray National Bird Refuge

See also: List of National Wildlife Refuges