The following is a compilation of people who have mysteriously disappeared, whose death is not substantiated, or whose whereabouts are unknown and who may be presumed deceased.

• Princes in the Tower sons of King Edward IV of England - 1483
• Dorothy Arnold - Manhattan socialite - 1910
• Benjamin Bathurst - British envoy - 1809
• Ambrose Bierce - Author - 1913
• Hale Boggs - American Congressman - 1972
• D. B. Cooper - skyjacker - 1971
• Joseph F. Crater - Associate Justice of the New York State Supreme Court - 1930
• Amelia Earhart - aviator - 1937
• Richey James Edwards - member of Welsh rock band the Manic Street Preachers
• Wallace D. Fard - Nation of Islam leader - 1934
• Percy Fawcett - British archaeologist and explorer - 1925
• Andrew Fluegelman - programmer, considered the father of shareware business - 1985
• Jesús María de Galíndez - scholar and activist - 1956
• Tooker Gomberg - Canadian politician and activist - 2004
• Richard Halliburton - author and adventurer - 1939
• Jimmy Hoffa - Union leader - 1975
• Harold Holt - Australian Prime Minister - 1967
• Osama bin Laden - terrorist - 2001
• Philip Christoph von Königsmarck, Swedish count, lover of George I of Great Britain's wife Sophia, Princess of Zelle - 1694
• Lord Lucan - dapper murder suspect - 1974
• Ettore Majorana, Italian mathematician - 1938
• Glenn Miller - bandleader - 1944
• Michael Rockefeller - son of Nelson Rockefeller - 1961
• Antoine de Saint-Exupéry - author and aviator - 1944
• Charles Carroll Taylor - leader of Flight 19 - 1945
• Jim Thompson - designer famous for Thai silks - 1967
• Francois Villon - French author-provocateur - 1465
• Andrew Carnegie Whitfield - nephew of Andrew Carnegie - 1938
• Persons missing after the September 11, 2001 attacks