Ketoacidosis is a type of metabolic acidosis which is caused by high concentrations of keto acids, formed by the deamination of amino acids. This is most common in untreated Type 1 diabetes, when the liver breaks down proteins in response to a perceived need for respiratory substrate.
The acidity results from the dissociation of the H+ ion at physiological pH of metabolic Ketone Bodies such as Acetoacetate, and B-hydroxybutyrate , produced from ketogenesis.
The Merck Manual -
- Diabetic Ketoacidosis http://www.merck.com/mrkshared/mmanual/section2/chapter13/13b.jsp
- Alcoholic Ketoacidosis http://www.merck.com/mrkshared/mmanual/section2/chapter13/13c.jsp
Last updated: 02-07-2005 06:29:56
Last updated: 05-03-2005 17:50:55