Hunain ibn Ishaq (809—873) was Nestorian physician in the House of Wisdom. He translated many treatises of Galen and the Galenic school into Syriac, and thirty-nine into Arabic; through his renderings some important works of Galen escaped destruction. Hunain also translated Aristotle's Categories, Physics, and Magna Moralia; Plato’s Republic, Timaeus, and Laws; Hippocrates’ Aphorisms, Dioscorides’ Materia Medica, Ptolemy's quadri-partition , and the Old Testament from the Septuagint Greek.

His son Ishaq ibn Hunain helped him with his translations.