The initials GPA can refer, among other things, to

• Grade Point Average; see Grade (education)
• Guinness Peat Aviation
• General Practice Australia, a private, independent medical accreditation society
• Greyhound Pets of America
• gigapascal (GPa) A unit of pressure
• Golden Party Armour A slang, though officially recognized and used term for the leather jackets worn by Applied Science (Engineering) Students at Queen's University