ER or er may stand for:
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Elizabeth Regina (Elizabeth the Queen); see Elizabeth I of England and Elizabeth II of the United Kingdom.
- An emergency room in a hospital, wherein victims arrive in emergency situations (usually by ambulance) or much to the dismay of emergency physicians and nurses, when they have a minor illness but are unable to see a family doctor.
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ER, a popular NBC medical drama set primarily in an emergency room.
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E/R, a less successful 1980s sitcom also set in an emergency room.
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The biblical figure Er, the eldest son of Judah.
- The endoplasmic reticulum in cell biology, which can be either rough or smooth.
- An entity-relationship diagram, which is a way of visualizing a database's table layout.
- The ISO country code for Eritrea.
- The chemical symbol for Erbium.
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Er (Р), a letter in the Cyrillic alphabet.
- The English sound "er," indicating hesistation, similar to huh and other speech disfluencies.
- In baseball, an earned run; a run that was scored without the aid of an error by the fielding team.
- In the Dutch_language, er has five different meanings.