Dr. Jekyll and Mr. Hyde is a 1931 adaptation of The Strange Case of Dr. Jekyll and Mr. Hyde, the Robert Louis Stevenson story of a man who takes a potion which turns him from a mild-mannered man of science into a crude homicidal maniac. It stars Fredric March, Miriam Hopkins, Rose Hobart , Holmes Herbert , Halliwell Hobbes and Edgar Norton .

The movie was adapted by Samuel Hoffenstein and Percy Heath and directed by Rouben Mamoulian.

It won the Academy Award for Best Actor (Fredric March, tied with Wallace Beery for The Champ). It was nominated for Best Cinematography and Best Writing, Adaptation.