CL may be:

• CAS Latency
• cathodoluminescence
• centilitre (cl)
• Central League (Japanese baseball)
• Chile (ISO country code)
• chlorine (Cl), symbol for the chemical element
• cl.exe Microsoft C/C++ command line compiler
• Colgate-Palmolive (NYSE stock symbol)
• Common Lisp
• Creative Loafing weekly
• Crédit Lyonnais bank
• light cruiser (US Navy)
• CL (OS/400 command interpreter)
• the IATA code for Lufthansa CityLine