Berkshire may refer to several places or subjects:

• In the United Kingdom: the county of Berkshire in southern England
• In the United States: (usually refers to a mountainous resort area in Massachusetts.)
  • Berkshire, New York
  • Berkshire, Vermont
  • Berkshire County, Massachusetts
  • Berkshire Mountains a range in Massachusetts and New York
• Berkshire Hathaway - an American investment and holding company
• A railroad steam locomotive type; in the Whyte notation, a Berkshire is a type 2-8-4
• There is also an Earldom of Berkshire, presently held by the Earl of Suffolk.