The Battle of Preveza (1538) was a naval battle fought between an Ottoman fleet commanded by Khair ad Din (Barbarossa) and a much larger allied fleet commanded by the great Genoese admiral Andrea Doria, near Preveza in northwest Greece. Barbarossa defeated the combined Spanish-Venetian fleet, thus making the Ottomans the leading Power in the Mediterranean Sea until their defeat at Battle of Lepanto in 1571.