B-17, Queen of the Skies is a wargame published in the US in 1983 by Avalon Hill and is a simulation of the experiences of a single B-17 Flying Fortress Bomber flying with the 8th Air Force in World War 2. It is designed for solitaire play, but there are rules for a two-player game. Game (mission) length can vary from 5 to 20 minutes depending on the target.

Several variants exist including a 15th Air Force variant. This game is also adaptable to a more role-playing game style of play.

Note that the bombers and crews in this simulation suffer from unusually high casualty rates. This was done to make the games more exciting, but it makes achieving the ultimate goal of surviving 25 missions virtually impossible.