Arrowsmith is a novel by American author Sinclair Lewis that was published in 1925. It tells the story of a young Dr. Martin Arrowsmith as he faces a disease outbreak on a Caribbean island.

The rock band Aerosmith did not take their name from the book. Drummer Joey Kramer, liked the combination of the prefix 'Aero' and 'Smith' and would doodle it on his high school binder.