The idea of an "all fifths" tuning for guitar, while perhaps intellectually satisfying, denies the physics of guitar strings. It is impossible, for all practical purposes, to tune any currently manufactured guitar string up to the high B assumed in this tuning. Transposing lower (below the suggested C) moves below the resonant frequencies of the acoustic guitar body. The New Standard Tuning of Guitar Craft (C-G-D-A-E-G, low to high)is the most practical approach to a predominantly fifths-based tuning.