The 1945 World Series matched the American League Detroit Tigers against the National League Chicago Cubs.

The Tigers won the Series, 4 games to 3, giving them their second championship, their first since 1935.

• Frank Graham jokingly called this Series "the fat men versus the tall men at the office picnic." It is the last time to date that the Chicago Cubs have appeared in the Series.

• The Curse of the Billy Goat was allegedly placed on the Cubs during this series. A fan wished to bring his goat into Wrigley Field. Spectators complained and had the man ejected. In response he placed a curse on the Cubs that they would never reach the World Series again. As of the 2005 season they have yet to do so.

Umpires: Bill Summers (AL), Lou Jorda (NL), Art Passarella (AL), Jocko Conlan (NL)