The year 1627 in science and technology consisted of many events, some of which are listed below.

See also: 1626 in science, other events of 1627, 1628 in science, and the list of years in science.

Astronomy

Exploration

• The Dutch ship the Gulden Zeepaert, skippered by Francois Thijssen, sails along the south coast of Australia

Medicine

Physics

Births

• January 25 - Robert Boyle, a founder of modern chemistry (died 1691)
• November 29 - John Ray, English naturalist (died 1705)

Deaths